High Rab27A expression indicates favorable prognosis in CRC
نویسندگان
چکیده
منابع مشابه
High Rab27A expression indicates favorable prognosis in CRC
BACKGROUND Rab27A is a peculiar member in Rab family and has been suggested to play essential roles in the development of human cancers. However, the association between Rab27A expression and clinicopathological characteristics of colorectal cancer (CRC) has not been elucidated yet. METHODS One-step quantitative real-time polymerase chain reaction (qPCR) test with 18 fresh-frozen CRC samples ...
متن کاملCD44 expression indicates favorable prognosis in epithelial ovarian cancer.
PURPOSE The purpose of this study was to investigate the expression and prognostic significance of CD44 in epithelial ovarian cancer. EXPERIMENTAL DESIGN We analyzed the expression of CD44 by immunohistochemistry in 307 epithelial ovarian cancers and evaluated its relation to hyaluronan, clinicopathological factors, and prognosis. RESULTS Fifty-one percent of the tumors had a high proportio...
متن کاملHigh expression of ABCC1 indicates poor prognosis in intrahepatic cholangiocarcinoma.
Intrahepatic cholangiocarcinoma (ICC) is a serious health problem in Thailand. To reach a cure, radical resection is the gold standard but most patients are not candidates because of delayed first presentation. Palliative surgery and/or combined chemotherapy are alternatives; however, outcomes are still unsatisfactory. A low response to multiple anticancer drugs might be due to a multidrug resi...
متن کاملHigh expression of TAZ indicates a poor prognosis in retinoblastoma
BACKGROUND The transcriptional co-activator, TAZ, is an important effector of the Hippo pathway and is critical for the development of human cancers. However, the expression and prognostic significance of TAZ in retinoblastoma is currently unclear. METHODS TAZ expression was examined in 43 retinoblastoma samples by immunohistochemistry. The relationship between TAZ expression and the clinicop...
متن کاملHigh USP22 expression indicates poor prognosis in hepatocellular carcinoma
Ubiquitin-specific protease 22 (USP22) removes ubiquitin from histones, thus regulating gene transcription. The expression frequency and expression levels of USP22 were significantly higher in hepatocellular carcinoma (HCC) than in normal liver tissues. High USP22 expression in HCC was significantly correlated with clinical stage and tumor grade. Kaplan-Meier analysis showed that elevated USP22...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diagnostic Pathology
سال: 2015
ISSN: 1746-1596
DOI: 10.1186/s13000-015-0303-3